![]() The vessel density measurement of macular scan by mean of optical coherence tomography angiography demonstrated good repeatability. Optical coherence tomography angiography is a useful modality to visualise the microvasculature plexus of macula and optic nerve head. Likewise, the coefficient of variation of optic disc scans, for right and left eyes, ranged from 14.3 to 77.4% and 13.5 to 75.3%. The measurement repeatability tests showed that the coefficient of variation of macular scans, for right and left eyes, ranged from 6.4 to 31.1% and 5.3 to 59.4%. For optic disc images, mean vessel density at vitreoretinal interface, radial peripapillary capillary, superficial nerve head and disc segment at the level of choroid were OD 0.084 and OS 0.085, OD 0.140 and OS 0.138, OD 0.216 and OS 0.209, OD 0.227 and OS 0.236 respectively. For macular images, the mean vessel density at superficial retina, deep retina, outer retina and choriocapillaries segment was OD 0.113 and OS 0.111, OD 0.239 and OS 0.230, OD 0.179 and OS 0.164, OD 0.237 and OS 0.215 respectively. ResultsĪ total of 176 eyes from 88 consecutive normal subjects were recruited. Data were analysed to determine the measurement repeatability. Novel in-house developed software was used to count the pixels in each images and to compute the microvessel density of the macula and optic disc. Two sets of optical coherence tomography angiography images of macula and optic nerve head were acquired during one visit. Subjects with normal eyes were recruited. MethodsĬross sectional observational cohort study. This study set out to measure the microvascular density of macula and optic disc by mean of optical coherence tomography angiography and report the repeatability of the vessel density measurements. Despite the potential usefulness of optical coherence tomography angiography in retinal and optic disc conditions, the reliability of the imaging modality remains unclear.
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